Tuesday, October 25, 2016

Cyperguard




Cyperguard may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Cyperguard



Cypermethrin

Cypermethrin is reported as an ingredient of Cyperguard in the following countries:


  • Ireland

International Drug Name Search

denosumab


Generic Name: denosumab (Xgeva) (den OH sue mab)

Brand Names: Xgeva


What is denosumab (Xgeva)?

Denosumab is a monoclonal antibody. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.


The Xgeva brand of denosumab is used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. Xgeva is not for use in people with multiple myeloma (bone marrow cancer).


This medication guide provides information about the Xgeva brand of denosumab. Prolia is another brand of denosumab used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.


Denosumab may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Xgeva?


This medication guide provides information about the Xgeva brand of denosumab. Prolia is another brand of denosumab used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.


You should not receive denosumab if you are allergic to it, or if you have low levels of calcium in your blood (hypocalcemia).

Before you receive this medication, tell your doctor if you have kidney disease or if you are on dialysis.


Some people using denosumab have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.


If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are receiving denosumab. You may need to stop using the medicine for a short time.

What should I discuss with my healthcare provider before receiving Xgeva?


You should not receive denosumab if you are allergic to it, or if you have low levels of calcium in your blood (hypocalcemia).

To make sure you can safely use Xgeva, tell your doctor if you have kidney disease or if you are on dialysis.


FDA pregnancy category C. It is not known whether denosumab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of denosumab on the baby. It is not known whether denosumab passes into breast milk or if it could harm a nursing baby. However, this medication may slow the production of breast milk. You should not breast-feed while receiving denosumab.

Some people using denosumab have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.


How is Xgeva given?


Denosumab is injected under the skin of your stomach, upper thigh, or upper arm. A healthcare provider will give you this injection.


Xgeva is usually given once every 4 weeks. Follow your doctor's instructions.


Your doctor may have you take extra calcium and vitamin D while you are being treated with denosumab. Take only the amount of calcium and vitamin D that your doctor has prescribed.


Pay special attention to your dental hygiene. Brush and floss your teeth regularly while receiving this medication. You may need to have a dental exam before you begin treatment with Xgeva. Follow your doctor's instructions.


If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are receiving denosumab. You may need to stop using the medicine for a short time. If you keep your medication at home, store it in the original container in a refrigerator. Protect from light and do not freeze.

You may take the medicine out of the refrigerator and allow it to reach room temperature before giving the injection. Do not heat the medicine before using.


After you have taken Xgeva out of the refrigerator, you may keep it at room temperature and use it within 14 days. Store in the original container away from heat and light. Do not shake the medication bottle or you may ruin the medicine. Prepare your dose in a syringe only when you are ready to give yourself an injection. Do not use the medication if it looks cloudy or has particles in it. Call your doctor for a new prescription.

Each single use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.


What happens if I miss a dose?


Call your doctor for instructions if you miss an appointment for your Xgeva injection.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while receiving Xgeva?


Follow your doctor's instructions about any restrictions on food, beverages, or activity.


Xgeva side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • numbness or tingly feeling around your mouth or in your fingers or toes, fast or slow heart rate, muscle cramps or contraction, overactive reflexes; or




  • trouble breathing.



Less serious side effects may include:



  • feeling weak or tired;




  • diarrhea, nausea; or




  • headache.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Denosumab Dosing Information


Usual Adult Dose for Osteoporosis:

For the treatment of postmenopausal women with osteoporosis at high risk for fracture, defined as a history of osteoporotic fracture, or multiple risk factors for fracture; or patients who have failed or are intolerant to other available osteoporosis therapy, treatment to increase bone mass in women at high risk for fracture
receiving adjuvant aromatase inhibitor therapy for breast cancer, and treatment to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for nonmetastatic prostate cancer:

60 mg administered as a single subcutaneous injection in the upper arm, the upper thigh, or the abdomen once every 6 months. All patients should receive calcium 1000 mg daily and at least 400 IU vitamin D daily

Usual Adult Dose for Hypercalcemia of Malignancy:

For the prevention of skeletal related events in patients with bone metastases from solid tumors:

120 mg as a subcutaneous injection in the upper arm, upper thigh, or abdomen every 4 weeks.

Administer calcium and vitamin D as necessary to treat or prevent hypocalcemia.


What other drugs will affect Xgeva?


There may be other drugs that can interact with Xgeva. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More denosumab resources


  • Denosumab Side Effects (in more detail)
  • Denosumab Use in Pregnancy & Breastfeeding
  • Denosumab Drug Interactions
  • Denosumab Support Group
  • 0 Reviews for Denosumab - Add your own review/rating


Compare denosumab with other medications


  • Hypercalcemia of Malignancy
  • Osteolytic Bone Metastases of Solid Tumors
  • Osteoporosis


Where can I get more information?


  • Your doctor or pharmacist can provide more information about denosumab (Xgeva).

See also: denosumab side effects (in more detail)


Alaceril




Alaceril may be available in the countries listed below.


Ingredient matches for Alaceril



Alacepril

Alacepril is reported as an ingredient of Alaceril in the following countries:


  • Japan

International Drug Name Search

Monday, October 24, 2016

Didanosine Delayed-Release Enteric-Coated Capsules


Pronunciation: dye-DAN-oh-seen
Generic Name: Didanosine
Brand Name: Videx EC

Didanosine Delayed-Release Enteric-Coated Capsules may cause serious and sometimes fatal inflammation of the pancreas (pancreatitis). This has occurred in patients who have just started taking Didanosine Delayed-Release Enteric-Coated Capsules and in patients who have already been taking it. Contact your doctor right away if you experience sudden stomach or back pain, swelling of the stomach, fever or chills, nausea or vomiting, or fast heartbeat.


Didanosine Delayed-Release Enteric-Coated Capsules may cause severe and sometimes fatal lactic acidosis and liver problems. Fatal lactic acidosis has also occurred in pregnant women who have used Didanosine Delayed-Release Enteric-Coated Capsules along with certain other medicines for HIV (eg, stavudine). Tell your doctor if you are taking stavudine and you are pregnant or planning to become pregnant.





Didanosine Delayed-Release Enteric-Coated Capsules are used for:

Treating HIV infection when used in combination with other medicines.


Didanosine Delayed-Release Enteric-Coated Capsules are a nucleoside analogue reverse transcriptase inhibitor. It works by stopping the growth of HIV-1, the virus that causes AIDS.


Do NOT use Didanosine Delayed-Release Enteric-Coated Capsules if:


  • you are allergic to any ingredient in Didanosine Delayed-Release Enteric-Coated Capsules

  • you have pancreas inflammation (pancreatitis), certain liver problems (eg, enlarged liver, portal hypertension), abnormal liver function tests, or lactic acidosis

  • you are taking allopurinol or ribavirin

Contact your doctor or health care provider right away if any of these apply to you.



Before using Didanosine Delayed-Release Enteric-Coated Capsules:


Some medical conditions may interact with Didanosine Delayed-Release Enteric-Coated Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of heart problems (eg, heart attack)

  • if you have advanced HIV infection (AIDS), kidney problems, liver problems (eg, hepatitis), gallstones, nerve problems (neuropathy), high blood cholesterol or lipid levels, or high blood amylase levels

  • if you are overweight or you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Didanosine Delayed-Release Enteric-Coated Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Hydroxyurea because the risk of pancreatitis may be increased

  • Allopurinol, ganciclovir, nucleotide reverse transcriptase inhibitors (eg, tenofovir), or ribavirin because they may increase the risk of Didanosine Delayed-Release Enteric-Coated Capsules's side effects

  • Methadone because it may decrease Didanosine Delayed-Release Enteric-Coated Capsules's effectiveness

  • Aluminum salts (eg, aluminum hydroxide) because the risk of their side effects may be increased by Didanosine Delayed-Release Enteric-Coated Capsules

  • Azole antifungals (eg, itraconazole, ketoconazole), delavirdine, HIV protease inhibitors (eg, indinavir, lopinavir, nelfinavir), lithium, quinolones (eg, ciprofloxacin, levofloxacin), sulfones (eg, dapsone), or tetracyclines (eg, doxycycline) because their effectiveness may be decreased by Didanosine Delayed-Release Enteric-Coated Capsules

  • Stavudine because the risk of pancreatitis or fatal lactic acidosis in pregnant women may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Didanosine Delayed-Release Enteric-Coated Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Didanosine Delayed-Release Enteric-Coated Capsules:


Use Didanosine Delayed-Release Enteric-Coated Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Didanosine Delayed-Release Enteric-Coated Capsules comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Didanosine Delayed-Release Enteric-Coated Capsules refilled.

  • Take Didanosine Delayed-Release Enteric-Coated Capsules by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

  • Swallow Didanosine Delayed-Release Enteric-Coated Capsules whole. Do not break, crush, or chew before swallowing.

  • Didanosine Delayed-Release Enteric-Coated Capsules may reduce the effectiveness of certain other medicines when taken together. Ask your doctor or pharmacist if you should separate Didanosine Delayed-Release Enteric-Coated Capsules from any other medicine that you are taking.

  • Continue to take Didanosine Delayed-Release Enteric-Coated Capsules even if you feel well. Do not miss any doses.

  • If you miss a dose of Didanosine Delayed-Release Enteric-Coated Capsules, take it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. It is important not to miss doses of Didanosine Delayed-Release Enteric-Coated Capsules. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Didanosine Delayed-Release Enteric-Coated Capsules.



Important safety information:


  • Do not drink alcohol while you are taking Didanosine Delayed-Release Enteric-Coated Capsules.

  • Didanosine Delayed-Release Enteric-Coated Capsules are not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.

  • Didanosine Delayed-Release Enteric-Coated Capsules does not stop the spread of HIV to others through blood or sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.

  • When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Didanosine Delayed-Release Enteric-Coated Capsules, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.

  • Tell your doctor or dentist that you take Didanosine Delayed-Release Enteric-Coated Capsules before you receive any medical or dental care, emergency care, or surgery.

  • The risk of severe side effects (eg, lactic acidosis, severe liver problems) may be greater in women, patients who are overweight (obese), and patients who have taken reverse transcriptase inhibitors (eg, emtricitabine, tenofovir) for a long time. Talk with your doctor if you have questions about your risk of severe side effects from Didanosine Delayed-Release Enteric-Coated Capsules.

  • Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Didanosine Delayed-Release Enteric-Coated Capsules. The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.

  • Didanosine Delayed-Release Enteric-Coated Capsules may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice symptoms of infection (eg, fever, sore throat, weakness, cough, shortness of breath) after you start Didanosine Delayed-Release Enteric-Coated Capsules.

  • Lab tests, including eye exams, liver function, complete blood cell counts, and blood clotting (eg, international normalized ratio [INR]), may be performed while you use Didanosine Delayed-Release Enteric-Coated Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Didanosine Delayed-Release Enteric-Coated Capsules with caution in the ELDERLY; they may be more sensitive to its effects.

  • Use Didanosine Delayed-Release Enteric-Coated Capsules with extreme caution in CHILDREN weighing less than 44 lb; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Didanosine Delayed-Release Enteric-Coated Capsules while you are pregnant. It is not known if Didanosine Delayed-Release Enteric-Coated Capsules are found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Didanosine Delayed-Release Enteric-Coated Capsules to the baby.


Possible side effects of Didanosine Delayed-Release Enteric-Coated Capsules:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Breast enlargement; changes in body fat; darkened complexion with purple markings; diarrhea; dry mouth; headache; itching; muscle pain; skin and facial wasting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in the vomit or vomit that looks like coffee grounds; blurred vision or other vision changes; chest pain or discomfort, numbness of an arm or leg, or shortness of breath; confusion; dark urine; dizziness; fainting; fast, shallow breathing; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; lightheadedness; low body temperature; nausea or vomiting; numbness, tingling, or pain in the hands or feet; pale stools; seizures; severe muscle pain or cramping; stomach pain or swelling; tiredness; unusual bruising or bleeding; weakness; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Didanosine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dark urine; diarrhea; pale stools; severe stomach pain with nausea and vomiting; tingling, burning, or numbness in the hands or feet; unusual fatigue; yellowing of the skin or eyes.


Proper storage of Didanosine Delayed-Release Enteric-Coated Capsules:

Store Didanosine Delayed-Release Enteric-Coated Capsules at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in a tightly closed container. Brief storage at temperatures of up to 86 degrees F (30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Didanosine Delayed-Release Enteric-Coated Capsules out of the reach of children and away from pets.


General information:


  • If you have any questions about Didanosine Delayed-Release Enteric-Coated Capsules, please talk with your doctor, pharmacist, or other health care provider.

  • Didanosine Delayed-Release Enteric-Coated Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Didanosine Delayed-Release Enteric-Coated Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Didanosine resources


  • Didanosine Side Effects (in more detail)
  • Didanosine Use in Pregnancy & Breastfeeding
  • Drug Images
  • Didanosine Drug Interactions
  • Didanosine Support Group
  • 0 Reviews for Didanosine - Add your own review/rating


Compare Didanosine with other medications


  • HIV Infection
  • Nonoccupational Exposure

Cabergolin Teva




Cabergolin Teva may be available in the countries listed below.


Ingredient matches for Cabergolin Teva



Cabergoline

Cabergoline is reported as an ingredient of Cabergolin Teva in the following countries:


  • Denmark

  • Malta

International Drug Name Search

Deprozol




Deprozol may be available in the countries listed below.


Ingredient matches for Deprozol



Secnidazole

Secnidazole is reported as an ingredient of Deprozol in the following countries:


  • Brazil

International Drug Name Search

Friday, October 21, 2016

Opipram




Opipram may be available in the countries listed below.


Ingredient matches for Opipram



Opipramol

Opipramol dihydrochloride (a derivative of Opipramol) is reported as an ingredient of Opipram in the following countries:


  • Germany

International Drug Name Search